SHOULDER

Help your rotator cuff injury heal

REGENETEN^◊ Bioinductive Implant

To ease your shoulder discomfort and get back to the things you love, discover a different way of treating rotator cuff tears.

What is the REGENETEN Implant?

The REGENETEN Bioinductive Implant is a small collagen patch designed to heal tears in the rotator cuff. It can be used on its own as an alternative to standard treatment or applied on top of a standard repair for:

Partial-thickness tears (when the tendon is partly damaged but not torn all the way through). The REGENETEN Implant is most commonly used on its own
Full-thickness tears (when the tendon is torn completely from one side to the other). The REGENETEN Implant is fixed on top of a repair using sutures and anchors

Once attached to your rotator cuff tendon during surgery, the REGENETEN Implant serves as a ‘scaffold’ for your tendon to grow new tissue and heal.^1-7

Is the REGENETEN Implant right for you?

To find out if the REGENETEN implant is a treatment option, make an appointment with an orthopaedic surgeon. The surgeon will examine your shoulder and review your health situation in determining if rotator cuff repair is recommended. To find a surgeon use our locator

Find a specialist

What can the REGENETEN Implant do for you?

More than 250,000 patients have had rotator cuff tendons repaired with the REGENETEN Implant. Learn how it might help you restore function in your shoulder.

Things to know about the REGENETEN Implant

Click/swipe through the sections below for a quick overview of key information.

Attached during surgery

Inserted into your shoulder using small arthroscopic incisions and attached to your rotator cuff using tissue and bone staples.

Helps new tissue grow

The collagen acts as a ‘scaffold’ to help your body grow new tendon -like tissue to repair the damaged tendon. It makes the tendon about 2mm thicker over six months (on average).^1-8

Absorbed over time

Over the span of 6 months, the implant is absorbed and replaced by new tissue. **^4,5

For partial-thickness tears

Used as an isolated treatment to help the tendon heal and get you back to daily activities quicker than standard repair methods.^7-9

For full-thickness tears

Used an augment on top of sutures and anchors to help increase the chances of the tendon healing, compared to standard repairs alone.¹⁰

How the REGENETEN Implant works

To understand how the REGENETEN Implant can help your rotator cuff tear, take a closer look at how it’s applied in surgery and how it works.

What are the types of rotator cuff repairs?

The traditional repair for a rotator cuff tear involves suturing the torn tendon and using anchors to reattach it to the arm bone. The REGENETEN implant offers two newer options for treatment. It may be used on its own as an alternative to standard treatment or applied as an addition to a standard repair.

Blog: Patient recovery stories

Frequently asked questions (FAQs)

How do I know if my surgeon uses the REGENETEN Implant?

You can use our surgeon locator to find a specialist who does. Please talk to your surgeon about your condition and treatment options, and whether the REGENETEN Implant should be considered as an option for you. Only your surgeon may determine whether the REGENETEN Implant is right for you. If you wish to find surgeons that have knowledge about Smith+Nephew technologies, you can access our surgeon locator for additional information.

Do I need to have a REGENETEN Implant removed?

No. It is made of a natural material and will be absorbed by your body.¹²

What’s in a REGENETEN Implant?

It’s made of type I collagen, which already occurs in the body. It is purified to a high medical grade standard in our manufacturing process.

Supporting Information

Important safety information

Risks

All surgery has risks and the potential for complications. Talk to your surgeon about any concerns you may have before you decide on treatment. Some of the possible risks and complications for rotator cuff repairs include: blood clotting, infection, pneumonia, nerve problems, long-term pain and stiffness in the shoulder, and rotator cuff re-tear.

This is not a complete list of risks. In some cases, you may need additional surgery to address a complication. Talk to your surgeon about the possible risks for your specific health situation, and whether any treatments referred to may be suitable for you and your condition, including the REGENETEN Implant, and of the associated risks, benefits and possible outcomes.

Please note

All information provided on this website is for informational purposes only and is not meant as medical advice. Not everyone is a candidate for rotator cuff repair using the REGENETEN^◊ Bioinductive Implant, and individual results of surgery may vary. Every patient’s case is unique, and each patient sho uld fo llow his or her doctor’s specific instructions. Please discuss nutrition, medication, and treatment options with your doctor to make sure you are getting the proper care for your particular situation. If you are seeking this information in an emergency, please call 911 and seek emergency
help.

Disclaimers

*Compared to standard repair methods. With specific reference to reference 9 (Wang et al, 2026), rehabilitation protocols differed between treatment groups: isolated REGENETEN Implant use employed a faster post-op rehab protocol vs traditional repair.

**On human biopsy (n=1) and in-vivo sampling.

The patient(s) featured in the videos may have been compensated by Smith+Nephew for their time.

The patient testimonial(s) depicted represent the individual patient’s own opinions, findings, beliefs, and/or experiences. Individual results will vary. Not everyone who receives a product or treatment will experience the same or similar results; results may vary depending on a number of facto rs, including each patient’s specific circumstances and condition, and compliance with the applicable Instructions for Use.

Smith+Nephew is not responsible for the selection of any treatment by a healthcare professional to be used on a particular patient. Smith+Nephew makes no representations, warranties, guarantees or assurances as to the availability, accuracy, currency or completeness of the information presented or its contents.

Products may not be available in all markets because product availability is subject to the regulatory and/or medical practices in individual markets. Please contact your
Smith+Nephew representative or distributor if you have questions about the availability of Smith+Nephew products in your area. For detailed product information, including indications for use, contraindications, precautions and warnings, please consult the pro duct’s applicable Instructions for Use (IFU) prior to use.

Citations

Bokor DJ, Sonnabend D, Deady L, et al. Muscles, Ligaments Tendons J 2016;6(1):16-25.
Schlegel TF, Abrams JS, Bushnell BD, Brock JL, Ho CP. J Shoulder Elbow Surg. 2018 27(2):242-251.
Thon SG, O’Malley L, O’Brien MJ, S avo ie FH. Am J Sports Med 2019;47(8):1901-1908.
Van Kampen C, Arnoczky S, Parks P, et al. Muscles Ligaments Tendons J. 2013;3(3):229-235.
Arnoczky SP, Bishai SK, Schofield B, et al. Arthroscopy. 2017;33(2):278-283.
Camacho-Chacon JA, et al. J Exp Orthop. 2022;9(1):53.
Camacho Chacon JA, et al. J Shoulder Elbow Surg. 2024;33(9):1894-1904.
Bushnell BD, et al. Orthop J Sports Med. 2021;9(8):23259671211027850.
Wang A, et al. Orthop J Sports Med. 2026 Mar 4;14(3):23259671261418675.
Ruiz Iban MA, et al. Arthroscopy 2024;40(6):1760-1773.
Parikh N, et al Curr Med Res Opin. 2021;37(7):1199-1211.
Smith+Nephew 2020. Internal Report. 15009769.

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